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TLR4-Dependent DUOX2 Activation Triggered Oxidative Stress and Promoted HMGB1 Release in Dry Eye

Dry eye disease (DED) is one of the most common ocular surface diseases worldwide. DED has been characterized by excessive accumulation of reactive oxygen species (ROS), following significant corneal epithelial cell death and ocular surface inflammation. However, the key regulatory factor remains un...

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Detalles Bibliográficos
Autores principales: Wang, Bowen, Zeng, Hao, Zuo, Xin, Yang, Xue, Wang, Xiaoran, He, Dalian, Yuan, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8793023/
https://www.ncbi.nlm.nih.gov/pubmed/35096875
http://dx.doi.org/10.3389/fmed.2021.781616