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TLR4-Dependent DUOX2 Activation Triggered Oxidative Stress and Promoted HMGB1 Release in Dry Eye
Dry eye disease (DED) is one of the most common ocular surface diseases worldwide. DED has been characterized by excessive accumulation of reactive oxygen species (ROS), following significant corneal epithelial cell death and ocular surface inflammation. However, the key regulatory factor remains un...
Autores principales: | Wang, Bowen, Zeng, Hao, Zuo, Xin, Yang, Xue, Wang, Xiaoran, He, Dalian, Yuan, Jin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8793023/ https://www.ncbi.nlm.nih.gov/pubmed/35096875 http://dx.doi.org/10.3389/fmed.2021.781616 |
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