Cargando…
Tim-3 Relieves Experimental Autoimmune Encephalomyelitis by Suppressing MHC-II
Tim-3, an immune checkpoint inhibitor, is widely expressed on the immune cells and contributes to immune tolerance. However, the mechanisms by which Tim-3 induces immune tolerance remain to be determined. Major histocompatibility complex II (MHC-II) plays a key role in antigen presentation and CD4(+...
Autores principales: | , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8793033/ https://www.ncbi.nlm.nih.gov/pubmed/35095844 http://dx.doi.org/10.3389/fimmu.2021.770402 |