Cargando…

Tim-3 Relieves Experimental Autoimmune Encephalomyelitis by Suppressing MHC-II

Tim-3, an immune checkpoint inhibitor, is widely expressed on the immune cells and contributes to immune tolerance. However, the mechanisms by which Tim-3 induces immune tolerance remain to be determined. Major histocompatibility complex II (MHC-II) plays a key role in antigen presentation and CD4(+...

Descripción completa

Detalles Bibliográficos
Autores principales: Tang, Lili, Li, Ge, Zheng, Yang, Hou, Chunmei, Gao, Yang, Hao, Ying, Gao, Zhenfang, Mo, Rongliang, Li, Yuxiang, Shen, Beifen, Wang, Renxi, Wang, Zhiding, Han, Gencheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8793033/
https://www.ncbi.nlm.nih.gov/pubmed/35095844
http://dx.doi.org/10.3389/fimmu.2021.770402