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Tim-3 Relieves Experimental Autoimmune Encephalomyelitis by Suppressing MHC-II

Tim-3, an immune checkpoint inhibitor, is widely expressed on the immune cells and contributes to immune tolerance. However, the mechanisms by which Tim-3 induces immune tolerance remain to be determined. Major histocompatibility complex II (MHC-II) plays a key role in antigen presentation and CD4(+...

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Detalles Bibliográficos
Autores principales:	Tang, Lili, Li, Ge, Zheng, Yang, Hou, Chunmei, Gao, Yang, Hao, Ying, Gao, Zhenfang, Mo, Rongliang, Li, Yuxiang, Shen, Beifen, Wang, Renxi, Wang, Zhiding, Han, Gencheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8793033/ https://www.ncbi.nlm.nih.gov/pubmed/35095844 http://dx.doi.org/10.3389/fimmu.2021.770402

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