Bifunctional Iminophosphorane-Catalyzed Enantioselective Sulfa-Michael Addition to Unactivated α,β-Unsaturated Amides

[Image: see text] The first metal-free catalytic intermolecular enantioselective Michael addition to unactivated α,β-unsaturated amides is described. Consistently high enantiomeric excesses and yields were obtained over a wide range of alkyl thiol pronucleophiles and electrophiles under mild reactio...

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Detalles Bibliográficos
Autores principales: Rozsar, Daniel, Formica, Michele, Yamazaki, Ken, Hamlin, Trevor A., Dixon, Darren J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8793149/
https://www.ncbi.nlm.nih.gov/pubmed/34990142
http://dx.doi.org/10.1021/jacs.1c11898

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8793149/
https://www.ncbi.nlm.nih.gov/pubmed/34990142
http://dx.doi.org/10.1021/jacs.1c11898

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