Evidence of telomere attrition and a potential role for DNA damage in systemic sclerosis

BACKGROUND: To investigate the role of cell senescence in systemic sclerosis (SSc), we analyzed telomere shortening (TS) in SSc patients and the effect of targeting DNA damage in the bleomycin model of skin fibrosis. RESULTS: Telomere length (TL) in blood leukocytes of 174 SSc patients and 68 health...

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Detalles Bibliográficos
Autores principales: Usategui, Alicia, Municio, Cristina, Arias-Salgado, Elena G., Martín, María, Fernández-Varas, Beatriz, Del Rey, Manuel J., Carreira, Patricia, González, Antonio, Criado, Gabriel, Perona, Rosario, Pablos, José L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8793167/
https://www.ncbi.nlm.nih.gov/pubmed/35086525
http://dx.doi.org/10.1186/s12979-022-00263-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8793167/
https://www.ncbi.nlm.nih.gov/pubmed/35086525
http://dx.doi.org/10.1186/s12979-022-00263-2

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