Discovery of Novel Reductive Elimination Pathway for 10-Hydroxywarfarin

Coumadin (R/S-warfarin) anticoagulant therapy is highly efficacious in preventing the formation of blood clots; however, significant inter-individual variations in response risks over or under dosing resulting in adverse bleeding events or ineffective therapy, respectively. Levels of pharmacological...

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Detalles Bibliográficos
Autores principales: Pouncey, Dakota L., Barnette, Dustyn A., Sinnott, Riley W., Phillips, Sarah J., Flynn, Noah R., Hendrickson, Howard P., Swamidass, S. Joshua, Miller, Grover P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8793337/
https://www.ncbi.nlm.nih.gov/pubmed/35095511
http://dx.doi.org/10.3389/fphar.2021.805133

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8793337/
https://www.ncbi.nlm.nih.gov/pubmed/35095511
http://dx.doi.org/10.3389/fphar.2021.805133

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