Amoxicillin Haptenation of α-Enolase is Modulated by Active Site Occupancy and Acetylation

Allergic reactions to antibiotics are a major concern in the clinic. ß-lactam antibiotics are the class most frequently reported to cause hypersensitivity reactions. One of the mechanisms involved in this outcome is the modification of proteins by covalent binding of the drug (haptenation). Hence, i...

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Detalles Bibliográficos
Autores principales: González-Morena, Juan M., Sánchez-Gómez, Francisco J., Vida, Yolanda, Pérez-Inestrosa, Ezequiel, Salas, María, Montañez, María I., Altomare, Alessandra, Aldini, Giancarlo, Pajares, María A., Pérez-Sala, Dolores
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8793629/
https://www.ncbi.nlm.nih.gov/pubmed/35095517
http://dx.doi.org/10.3389/fphar.2021.807742

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8793629/
https://www.ncbi.nlm.nih.gov/pubmed/35095517
http://dx.doi.org/10.3389/fphar.2021.807742

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