Cargando…
Amoxicillin Haptenation of α-Enolase is Modulated by Active Site Occupancy and Acetylation
Allergic reactions to antibiotics are a major concern in the clinic. ß-lactam antibiotics are the class most frequently reported to cause hypersensitivity reactions. One of the mechanisms involved in this outcome is the modification of proteins by covalent binding of the drug (haptenation). Hence, i...
| Autores principales: | , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8793629/ https://www.ncbi.nlm.nih.gov/pubmed/35095517 http://dx.doi.org/10.3389/fphar.2021.807742 |