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Ubiquitin-Specific Protease 25 Aggravates Acute Pancreatitis and Acute Pancreatitis-Related Multiple Organ Injury by Destroying Tight Junctions Through Activation of The STAT3 Pathway

Ubiquitin-specific protease 25 (USP25) plays an important role in inflammation and immunity. However, the role of USP25 in acute pancreatitis (AP) is still unclear. To evaluate the role of USP25 in AP, we conducted research on clinical AP patients, USP25(wild-type(WT))/USP25 knockout (USP25(−/−)) mi...

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Detalles Bibliográficos
Autores principales: Liu, Zhengru, Qi, Mingming, Tian, Shan, Yang, Qian, Liu, Jian, Wang, Siwei, Ji, Mengyao, Yu, Rong, Zeng, Suqi, Li, Jinting, Wei, Yuping, Dong, Weiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8793747/
https://www.ncbi.nlm.nih.gov/pubmed/35096833
http://dx.doi.org/10.3389/fcell.2021.806850