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Chemopreventive and hepatoprotective effects of genistein via inhibition of oxidative stress and the versican/PDGF/PKC signaling pathway in experimentally induced hepatocellular carcinoma in rats by thioacetamide

OBJECTIVE: Genistein is a recognized isoflavone present in soybeans with antioxidant, anti-inflammatory, antiangiogenic and antitumor activities. This study aimed to test ability of genistein in modulating versican/platelet derived growth factor (PDGF) axis in HCC. METHODS: HCC was experimentally in...

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Detalles Bibliográficos
Autores principales: El-Far, Yousra M., Khodir, Ahmed E., Emarah, Ziad A., Ebrahim, Mohamed A., Al-Gayyar, Mohammed M. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8794077/
https://www.ncbi.nlm.nih.gov/pubmed/35080474
http://dx.doi.org/10.1080/13510002.2022.2031515