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Chemopreventive and hepatoprotective effects of genistein via inhibition of oxidative stress and the versican/PDGF/PKC signaling pathway in experimentally induced hepatocellular carcinoma in rats by thioacetamide
OBJECTIVE: Genistein is a recognized isoflavone present in soybeans with antioxidant, anti-inflammatory, antiangiogenic and antitumor activities. This study aimed to test ability of genistein in modulating versican/platelet derived growth factor (PDGF) axis in HCC. METHODS: HCC was experimentally in...
Autores principales: | El-Far, Yousra M., Khodir, Ahmed E., Emarah, Ziad A., Ebrahim, Mohamed A., Al-Gayyar, Mohammed M. H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8794077/ https://www.ncbi.nlm.nih.gov/pubmed/35080474 http://dx.doi.org/10.1080/13510002.2022.2031515 |
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