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Noise-augmented directional clustering of genetic association data identifies distinct mechanisms underlying obesity

Clustering genetic variants based on their associations with different traits can provide insight into their underlying biological mechanisms. Existing clustering approaches typically group variants based on the similarity of their association estimates for various traits. We present a new procedure...

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Detalles Bibliográficos
Autores principales: Grant, Andrew J., Gill, Dipender, Kirk, Paul D. W., Burgess, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8794082/
https://www.ncbi.nlm.nih.gov/pubmed/35085229
http://dx.doi.org/10.1371/journal.pgen.1009975