Nalaganje...
Loss of the transcription repressor ZHX3 induces senescence-associated gene expression and mitochondrial-nucleolar activation
Cellular senescence is accompanied by metabolic and epigenomic remodeling, but the transcriptional mechanism of this process is unclear. Our previous RNA interference-based screen of chromatin factors found that lysine methyltransferases including SETD8 and NSD2 inhibited the senescence program in c...
Autores principales: | , , , , , , |
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Format: | Online Artículo Texto |
Jezik: | English |
Izdano: |
Public Library of Science
2022
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Teme: | |
Online dostop: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8794122/ https://www.ncbi.nlm.nih.gov/pubmed/35085309 http://dx.doi.org/10.1371/journal.pone.0262488 |