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Impact of high platelet turnover on the platelet transcriptome: Results from platelet RNA-sequencing in patients with sepsis

BACKGROUND: Sepsis is associated with high platelet turnover and elevated levels of immature platelets. Changes in the platelet transcriptome and the specific impact of immature platelets on the platelet transcriptome remain unclear. Thus, this study sought to address whether and how elevated levels...

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Detalles Bibliográficos
Autores principales: Nührenberg, Thomas G., Stöckle, Jasmin, Marini, Federico, Zurek, Mark, Grüning, Björn A., Benes, Vladimir, Hein, Lutz, Neumann, Franz-Josef, Stratz, Christian, Cederqvist, Marco, Hochholzer, Willibald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8794123/
https://www.ncbi.nlm.nih.gov/pubmed/35085240
http://dx.doi.org/10.1371/journal.pone.0260222