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Cardiac forces regulate zebrafish heart valve delamination by modulating Nfat signaling
In the clinic, most cases of congenital heart valve defects are thought to arise through errors that occur after the endothelial–mesenchymal transition (EndoMT) stage of valve development. Although mechanical forces caused by heartbeat are essential modulators of cardiovascular development, their ro...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8794269/ https://www.ncbi.nlm.nih.gov/pubmed/35030171 http://dx.doi.org/10.1371/journal.pbio.3001505 |