Cardiac forces regulate zebrafish heart valve delamination by modulating Nfat signaling

In the clinic, most cases of congenital heart valve defects are thought to arise through errors that occur after the endothelial–mesenchymal transition (EndoMT) stage of valve development. Although mechanical forces caused by heartbeat are essential modulators of cardiovascular development, their ro...

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Detalles Bibliográficos
Autores principales: Chow, Renee Wei-Yan, Fukui, Hajime, Chan, Wei Xuan, Tan, Kok Soon Justin, Roth, Stéphane, Duchemin, Anne-Laure, Messaddeq, Nadia, Nakajima, Hiroyuki, Liu, Fei, Faggianelli-Conrozier, Nathalie, Klymchenko, Andrey S., Choon Hwai, Yap, Mochizuki, Naoki, Vermot, Julien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8794269/
https://www.ncbi.nlm.nih.gov/pubmed/35030171
http://dx.doi.org/10.1371/journal.pbio.3001505

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