Cargando…

M1 receptors interacting with NMDAR enhance delay-related neuronal firing and improve working memory performance

The recurrent excitatory circuits in dlPFC underlying working memory are known to require activation of glutamatergic NMDA receptors (NMDAR). The neurons in these circuits also rely on acetylcholine to maintain persistent activity, with evidence for actions at both nicotinic α7 receptors and muscari...

Descripción completa

Detalles Bibliográficos
Autores principales: Galvin, Veronica C., Yang, Shengtao, Lowet, Adam S., Datta, Dibyadeep, Duque, Alvaro, Arnsten, Amy FT., Wang, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8794314/
https://www.ncbi.nlm.nih.gov/pubmed/35098156
http://dx.doi.org/10.1016/j.crneur.2021.100016