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M1 receptors interacting with NMDAR enhance delay-related neuronal firing and improve working memory performance
The recurrent excitatory circuits in dlPFC underlying working memory are known to require activation of glutamatergic NMDA receptors (NMDAR). The neurons in these circuits also rely on acetylcholine to maintain persistent activity, with evidence for actions at both nicotinic α7 receptors and muscari...
Autores principales: | Galvin, Veronica C., Yang, Shengtao, Lowet, Adam S., Datta, Dibyadeep, Duque, Alvaro, Arnsten, Amy FT., Wang, Min |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8794314/ https://www.ncbi.nlm.nih.gov/pubmed/35098156 http://dx.doi.org/10.1016/j.crneur.2021.100016 |
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