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A phosphoswitch at acinus-serine(437) controls autophagic responses to cadmium exposure and neurodegenerative stress

Neuronal health depends on quality control functions of autophagy, but mechanisms regulating neuronal autophagy are poorly understood. Previously, we showed that in Drosophila starvation-independent quality control autophagy is regulated by acinus (acn) and the Cdk5-dependent phosphorylation of its...

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Detalles Bibliográficos
Autores principales: Nandi, Nilay, Zaidi, Zuhair, Tracy, Charles, Krämer, Helmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8794470/
https://www.ncbi.nlm.nih.gov/pubmed/35037620
http://dx.doi.org/10.7554/eLife.72169