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Stress conditions promote Leishmania hybridization in vitro marked by expression of the ancestral gamete fusogen HAP2 as revealed by single-cell RNA-seq

Leishmania are protozoan parasites transmitted by the bite of sand fly vectors producing a wide spectrum of diseases in their mammalian hosts. These diverse clinical outcomes are directly associated with parasite strain and species diversity. Although Leishmania reproduction is mainly clonal, a cryp...

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Detalles Bibliográficos
Autores principales: Louradour, Isabelle, Ferreira, Tiago Rodrigues, Duge, Emma, Karunaweera, Nadira, Paun, Andrea, Sacks, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8794473/
https://www.ncbi.nlm.nih.gov/pubmed/34994687
http://dx.doi.org/10.7554/eLife.73488