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Impact of the glutathione synthesis pathway on sulfasalazine-treated endometrial cancer

Glutathione is an antioxidant that has an important role in chemotherapeutic drug resistance in cancer. Cysteine is synthesized from cystine and is transported into the cell via the xCT antiporter. Another pathway for synthesizing cysteine involves intracellular methionine. We determined whether tar...

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Detalles Bibliográficos
Autores principales: Sendo, Kanako, Seino, Manabu, Ohta, Tsuyoshi, Nagase, Satoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8794577/
https://www.ncbi.nlm.nih.gov/pubmed/35106124
http://dx.doi.org/10.18632/oncotarget.28185