The Reduction of Tau Hyperphosphorylation by Cornel Iridoid Glycosides Is Mediated by Their Influence on Calpain Activity

Alzheimer's disease (AD) is the most common type of dementia, and the abnormal hyperphosphorylation of the tau protein is the main component of its pathogenesis. Calpain was found to be abnormally activated in neurofibrillary tangles (NFTs) in a previous report. Cornel iridoid glycosides (CIG)...

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Detalles Bibliográficos
Autores principales: Guo, Kaiwen, Yang, Cuicui, Zhang, Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8794656/
https://www.ncbi.nlm.nih.gov/pubmed/35096120
http://dx.doi.org/10.1155/2022/9213046

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8794656/
https://www.ncbi.nlm.nih.gov/pubmed/35096120
http://dx.doi.org/10.1155/2022/9213046

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