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Molecular Mechanism of Tetramethylpyrazine Ameliorating Neuroexcitotoxicity through Activating the PKA/CREB Signaling Pathway

BACKGROUND: Excitotoxicity plays a key role in nervous system disease and can trigger a critical cascade of reaction which affects cell viability and promotes neuronal death. Tetramethylpyrazine (TMP) reveals its effect in the treatment of neurovascular diseases by antiapoptosis. Recently, there wer...

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Detalles Bibliográficos
Autores principales: Tong, Hongxuan, Wang, Kaili, Wang, Xiting, Lu, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8794663/
https://www.ncbi.nlm.nih.gov/pubmed/35097116
http://dx.doi.org/10.1155/2022/2812839