Cargando…

Molecular Mechanism of Tetramethylpyrazine Ameliorating Neuroexcitotoxicity through Activating the PKA/CREB Signaling Pathway

BACKGROUND: Excitotoxicity plays a key role in nervous system disease and can trigger a critical cascade of reaction which affects cell viability and promotes neuronal death. Tetramethylpyrazine (TMP) reveals its effect in the treatment of neurovascular diseases by antiapoptosis. Recently, there wer...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tong, Hongxuan, Wang, Kaili, Wang, Xiting, Lu, Tao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8794663/ https://www.ncbi.nlm.nih.gov/pubmed/35097116 http://dx.doi.org/10.1155/2022/2812839

Ejemplares similares

Atraric Acid Ameliorates Hyperpigmentation through the Downregulation of the PKA/CREB/MITF Signaling Pathway
por: Li, Jing, et al.
Publicado: (2022)

Perampanel ameliorates nitroglycerin-induced migraine through inhibition of the cAMP/PKA/CREB signaling pathway in the trigeminal ganglion in rats
por: Zhai, QingLing, et al.
Publicado: (2023)

The initiator of neuroexcitotoxicity and ferroptosis in ischemic stroke: Glutamate accumulation
por: Fan, Genhao, et al.
Publicado: (2023)

Mechanisms Underlying the Antidepressant Response of Acupuncture via PKA/CREB Signaling Pathway
por: Jiang, Huili, et al.
Publicado: (2017)

Liraglutide exhibits anti-inflammatory activity through the activation of the PKA/CREB pathway
por: Wang, Li, et al.
Publicado: (2019)

Melanogenic Effects of Maclurin Are Mediated through the Activation of cAMP/PKA/CREB and p38 MAPK/CREB Signaling Pathways
por: Hwang, Young Sun, et al.
Publicado: (2019)

Effects of CREB1 gene silencing on cognitive dysfunction by mediating PKA-CREB signaling pathway in mice with vascular dementia
por: Han, Xin-Rui, et al.
Publicado: (2018)

PKA-CREB-BDNF signaling regulated long lasting antidepressant activities of Yueju but not ketamine
por: Xue, Wenda, et al.
Publicado: (2016)

Electroacupuncture Ameliorates Learning and Memory and Improves Synaptic Plasticity via Activation of the PKA/CREB Signaling Pathway in Cerebral Hypoperfusion
por: Zheng, Cai-Xia, et al.
Publicado: (2016)

Complex roles of cAMP–PKA–CREB signaling in cancer
por: Zhang, Hongying, et al.
Publicado: (2020)

The GLP-1 agonist, liraglutide, ameliorates inflammation through the activation of the PKA/CREB pathway in a rat model of knee osteoarthritis
por: Que, Qihong, et al.
Publicado: (2019)

TPM1 mediates inflammation downstream of TREM2 via the PKA/CREB signaling pathway
por: Li, Rong, et al.
Publicado: (2022)

The molecular biology of memory: cAMP, PKA, CRE, CREB-1, CREB-2, and CPEB
por: Kandel, Eric R
Publicado: (2012)

Retraction Note: Effects of CREB1 gene silencing on cognitive dysfunction by mediating PKA-CREB signaling pathway in mice with vascular dementia
por: Han, Xin-Rui, et al.
Publicado: (2023)

Tetramethylpyrazine ameliorates acute lung injury by regulating the Rac1/LIMK1 signaling pathway
por: Min, Simin, et al.
Publicado: (2023)

Lipid Supplement in the Cultural Condition Facilitates the Porcine iPSC Derivation through cAMP/PKA/CREB Signal Pathway
por: Zhang, Wei, et al.
Publicado: (2018)

Tetramethylpyrazine Produces Antidepressant-Like Effects in Mice Through Promotion of BDNF Signaling Pathway
por: Jiang, Bo, et al.
Publicado: (2015)

Cannabidiol attenuates methamphetamine-induced cardiac inflammatory response through the PKA/CREB pathway in rats
por: Nie, Qianyun, et al.
Publicado: (2022)

The PKA-CREB system encoded by the honeybee genome
por: Eisenhardt, D, et al.
Publicado: (2006)

Tetramethylpyrazine Ameliorates Peritoneal Angiogenesis by Regulating VEGF/Hippo/YAP Signaling
por: Zhu, Xiaolin, et al.
Publicado: (2021)

Calycosin, a Common Dietary Isoflavonoid, Suppresses Melanogenesis through the Downregulation of PKA/CREB and p38 MAPK Signaling Pathways
por: Wu, Kun-Chang, et al.
Publicado: (2022)

Cryptochrome 1 activation inhibits melanogenesis and melanosome transport through negative regulation of cAMP/PKA/CREB signaling pathway
por: Gao, Rongyin, et al.
Publicado: (2023)

Anthrax Edema Toxin Modulates PKA- and CREB-Dependent Signaling in Two Phases
por: Puhar, Andrea, et al.
Publicado: (2008)

cAMP Signaling in Cancer: A PKA-CREB and EPAC-Centric Approach
por: Ahmed, Muhammad Bilal, et al.
Publicado: (2022)

Neuroprotective and neurogenic effects of novel tetramethylpyrazine derivative T-006 in Parkinson’s disease models through activating the MEF2-PGC1α and BDNF/CREB pathways
por: Chen, Haiyun, et al.
Publicado: (2020)

β-Patchoulene Ameliorates Water Transport and the Mucus Barrier in 5-Fluorouracil-Induced Intestinal Mucositis Rats via the cAMP/PKA/CREB Signaling Pathway
por: Wu, Jiazhen, et al.
Publicado: (2021)

Imperatorin Positively Regulates Melanogenesis through Signaling Pathways Involving PKA/CREB, ERK, AKT, and GSK3β/β-Catenin
por: Kim, Taejin, et al.
Publicado: (2022)

Dopamine Receptors Modulate Cytotoxicity of Natural Killer Cells via cAMP-PKA-CREB Signaling Pathway
por: Zhao, Wei, et al.
Publicado: (2013)

Repeated exposure to sevoflurane in neonatal rats impairs cognition in adulthood via the PKA-CREB-BDNF signaling pathway
por: Zhao, Jili, et al.
Publicado: (2021)

Tetramethylpyrazine Inhibits Activation of Hepatic Stellate Cells through Hedgehog Signaling Pathways In Vitro
por: Hu, Jue, et al.
Publicado: (2015)

Correction: Anthrax Edema Toxin Modulates PKA- and CREB-Dependent Signaling in Two Phases
por: Puhar, Andrea, et al.
Publicado: (2008)

Anti-Melanogenic Effects of Lilium lancifolium Root Extract via Downregulation of PKA/CREB and MAPK/CREB Signaling Pathways in B16F10 Cells
por: Park, Seokmuk, et al.
Publicado: (2023)

Xingnao Jieyu Decoction Ameliorates Poststroke Depression through the BDNF/ERK/CREB Pathway in Rats
por: Li, Tao, et al.
Publicado: (2018)

Ebola virus VP35 hijacks the PKA-CREB1 pathway for replication and pathogenesis by AKIP1 association
por: Zhu, Lin, et al.
Publicado: (2022)

Sinapic acid induces the expression of thermogenic signature genes and lipolysis through activation of PKA/CREB signaling in brown adipocytes
por: Hossain, Monir, et al.
Publicado: (2020)

The Rapid and Long-Lasting Antidepressant Effects of Iridoid Fraction in Gardenia Jasminoides J.Ellis Are Dependent on Activating PKA-CREB Signaling Pathway
por: Ren, Li, et al.
Publicado: (2022)

Rhynchosia volubilis Promotes Cell Survival via cAMP-PKA/ERK-CREB Pathway
por: Ahn, Sang-Hyun, et al.
Publicado: (2022)

Jie-Yu-He-Huan Capsule Ameliorates Anxiety-Like Behaviours in Rats Exposed to Chronic Restraint Stress via the cAMP/PKA/CREB/BDNF Signalling Pathway
por: Geng, Xiwen, et al.
Publicado: (2021)

Anti-depressant effects of oil from fructus gardeniae via PKA-CREB-BDNF signaling
por: Ruan, Jie, et al.
Publicado: (2019)

6-Methylcoumarin Promotes Melanogenesis through the PKA/CREB, MAPK, AKT/PI3K, and GSK3β/β-Catenin Signaling Pathways
por: Kim, Taejin, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_trk1fsf911c71da5e357bkcdnu