Dapagliflozin Ameliorates STZ-Induced Cardiac Hypertrophy in Type 2 Diabetic Rats by Inhibiting the Calpain-1 Expression and Nuclear Transfer of NF-κB

OBJECTIVE: To investigate the effect of dapagliflozin (DAPA) on cardiac hypertrophy induced by type 2 diabetes mellitus (T2DM) and its mechanism. METHODS: SD rats with T2DM were divided into a T2DM group (n = 6) and DAPA group (n = 6). They were, respectively, fed with the same amount of normal sali...

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Detalles Bibliográficos
Autores principales: Liu, Lei, Luo, Haizhao, Liang, Yunyi, Tang, Jielong, Shu, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8794691/
https://www.ncbi.nlm.nih.gov/pubmed/35096128
http://dx.doi.org/10.1155/2022/3293054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8794691/
https://www.ncbi.nlm.nih.gov/pubmed/35096128
http://dx.doi.org/10.1155/2022/3293054

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