Macrophage Depletion Reduces Disease Pathology in Factor H-Dependent Immune Complex-Mediated Glomerulonephritis

Complement factor H (FH) is a key regulator of the alternative pathway of complement, in man and mouse. Earlier, our studies revealed that the absence of FH causes the C57BL6 mouse to become susceptible to chronic serum sickness (CSS) along with an increase in the renal infiltration of macrophages c...

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Detalles Bibliográficos
Autores principales: Jacob, Alexander, Phelps, Michael, Fraher, Shane, Lopez, Marcos, Chang, Anthony, Quigg, Richard J., Alexander, Jessy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8794693/
https://www.ncbi.nlm.nih.gov/pubmed/35097132
http://dx.doi.org/10.1155/2022/1737419

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8794693/
https://www.ncbi.nlm.nih.gov/pubmed/35097132
http://dx.doi.org/10.1155/2022/1737419

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