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Prediction of long-term kinetics of vaccine-elicited neutralizing antibody and time-varying vaccine-specific efficacy against the SARS-CoV-2 Delta variant by clinical endpoint

BACKGROUND: Evidence on vaccine-specific protection over time, in particular against the Delta variant, and protection afforded by a homologous third dose is urgently needed. METHODS: We used a previously published model and neutralization data for five vaccines—mRNA-1273, BNT162b2, NVX-CoV2373, V01...

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Detalles Bibliográficos
Autores principales: Chen, Xinhua, Wang, Wei, Chen, Xinghui, Wu, Qianhui, Sun, Ruijia, Ge, Shijia, Zheng, Nan, Lu, Wanying, Yang, Juan, Rodewald, Lance, Yu, Hongjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8794738/
https://www.ncbi.nlm.nih.gov/pubmed/35086547
http://dx.doi.org/10.1186/s12916-022-02249-9