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A compensatory link between cleavage/polyadenylation and mRNA turnover regulates steady-state mRNA levels in yeast

Cells have compensatory mechanisms to coordinate the rates of major biological processes, thereby permitting growth in a wide variety of conditions. Here, we uncover a compensatory link between cleavage/polyadenylation in the nucleus and messenger RNA (mRNA) turnover in the cytoplasm. On a global ba...

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Detalles Bibliográficos
Autores principales: Moqtaderi, Zarmik, Geisberg, Joseph V., Struhl, Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8794773/
https://www.ncbi.nlm.nih.gov/pubmed/35058367
http://dx.doi.org/10.1073/pnas.2121488119