Application of long-read sequencing to elucidate complex pharmacogenomic regions: a proof of principle

The use of pharmacogenomics in clinical practice is becoming standard of care. However, due to the complex genetic makeup of pharmacogenes, not all genetic variation is currently accounted for. Here, we show the utility of long-read sequencing to resolve complex pharmacogenes by analyzing a well-cha...

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Detalles Bibliográficos
Autores principales: van der Lee, Maaike, Rowell, William J., Menafra, Roberta, Guchelaar, Henk-Jan, Swen, Jesse J., Anvar, Seyed Yahya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8794781/
https://www.ncbi.nlm.nih.gov/pubmed/34741133
http://dx.doi.org/10.1038/s41397-021-00259-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8794781/
https://www.ncbi.nlm.nih.gov/pubmed/34741133
http://dx.doi.org/10.1038/s41397-021-00259-z

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