Obesity and Roux-en-Y gastric bypass drive changes in miR-31 and miR-215 expression in the human rectal mucosa

BACKGROUND/OBJECTIVES: Obesity increases colorectal cancer (CRC) risk. However, the effects of weight loss on CRC risk are unclear. Epigenetic mechanisms involving microRNAs that lead to dysregulated gene expression may mediate the effects of obesity and weight loss on CRC risk. We examined the effe...

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Detalles Bibliográficos
Autores principales: Breininger, Stella Panagio, Sabater, Laura, Malcomson, Fiona Caroline, Afshar, Sorena, Mann, Jelena, Mathers, John Cummings
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8794786/
https://www.ncbi.nlm.nih.gov/pubmed/34716428
http://dx.doi.org/10.1038/s41366-021-01005-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8794786/
https://www.ncbi.nlm.nih.gov/pubmed/34716428
http://dx.doi.org/10.1038/s41366-021-01005-y

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