Disruption of MeCP2–TCF20 complex underlies distinct neurodevelopmental disorders

MeCP2 is associated with Rett syndrome (RTT), MECP2 duplication syndrome, and a number of conditions with isolated features of these diseases, including autism, intellectual disability, and motor dysfunction. MeCP2 is known to broadly bind methylated DNA, but the precise molecular mechanism driving...

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Detalles Bibliográficos
Autores principales: Zhou, Jian, Hamdan, Hamdan, Yalamanchili, Hari Krishna, Pang, Kaifang, Pohodich, Amy E., Lopez, Joanna, Shao, Yingyao, Oses-Prieto, Juan A., Li, Lifang, Kim, Wonho, Durham, Mark A., Bajikar, Sameer S., Palmer, Donna J., Ng, Philip, Thompson, Michelle L., Bebin, E. Martina, Müller, Amelie J., Kuechler, Alma, Kampmeier, Antje, Haack, Tobias B., Burlingame, Alma L., Liu, Zhandong, Rasband, Matthew N., Zoghbi, Huda Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8794850/
https://www.ncbi.nlm.nih.gov/pubmed/35074918
http://dx.doi.org/10.1073/pnas.2119078119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8794850/
https://www.ncbi.nlm.nih.gov/pubmed/35074918
http://dx.doi.org/10.1073/pnas.2119078119

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