Mechanical disruption of E-cadherin complexes with epidermal growth factor receptor actuates growth factor–dependent signaling

Increased intercellular tension is associated with enhanced cell proliferation and tissue growth. Here, we present evidence for a force-transduction mechanism that links mechanical perturbations of epithelial (E)-cadherin (CDH1) receptors to the force-dependent activation of epidermal growth factor...

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Detalles Bibliográficos
Autores principales: Sullivan, Brendan, Light, Taylor, Vu, Vinh, Kapustka, Adrian, Hristova, Kalina, Leckband, Deborah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8794882/
https://www.ncbi.nlm.nih.gov/pubmed/35074920
http://dx.doi.org/10.1073/pnas.2100679119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8794882/
https://www.ncbi.nlm.nih.gov/pubmed/35074920
http://dx.doi.org/10.1073/pnas.2100679119

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