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Mechanical disruption of E-cadherin complexes with epidermal growth factor receptor actuates growth factor–dependent signaling
Increased intercellular tension is associated with enhanced cell proliferation and tissue growth. Here, we present evidence for a force-transduction mechanism that links mechanical perturbations of epithelial (E)-cadherin (CDH1) receptors to the force-dependent activation of epidermal growth factor...
Autores principales: | Sullivan, Brendan, Light, Taylor, Vu, Vinh, Kapustka, Adrian, Hristova, Kalina, Leckband, Deborah |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8794882/ https://www.ncbi.nlm.nih.gov/pubmed/35074920 http://dx.doi.org/10.1073/pnas.2100679119 |
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