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Triple-negative expression (ALDH1A1-/CD133-/mutant p53-) cases in lung adenocarcinoma had a good prognosis

Cancer stem cells (CSCs) are major contributors to the malignant transformation of cells because of their capacity for self-renewal. Aldehyde dehydrogenase1A1 (ALDH1A1) and CD133 are promising candidate of CSC markers in non-small cell lung cancer (NSCLC). Furthermore, TP53 is frequently mutated in...

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Detalles Bibliográficos
Autores principales: Yamashita, Naoki, So, Tetsuya, Miyata, Takeaki, Yoshimatsu, Takashi, Nakano, Ryuji, Oyama, Tsunehiro, Matsunaga, Wataru, Gotoh, Akinobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795115/
https://www.ncbi.nlm.nih.gov/pubmed/35087112
http://dx.doi.org/10.1038/s41598-022-05176-0