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Structures and function of a tailoring oxidase in complex with a nonribosomal peptide synthetase module

Nonribosomal peptide synthetases (NRPSs) are large modular enzymes that synthesize secondary metabolites and natural product therapeutics. Most NRPS biosynthetic pathways include an NRPS and additional proteins that introduce chemical modifications before, during or after assembly-line synthesis. Th...

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Detalles Bibliográficos
Autores principales: Fortinez, Camille Marie, Bloudoff, Kristjan, Harrigan, Connor, Sharon, Itai, Strauss, Mike, Schmeing, T. Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795117/
https://www.ncbi.nlm.nih.gov/pubmed/35087027
http://dx.doi.org/10.1038/s41467-022-28221-y