Restricted valency (NPNA)(n) repeats and junctional epitope-based circumsporozoite protein vaccines against Plasmodium falciparum

The Circumsporozoite Protein (CSP) of Plasmodium falciparum contains an N-terminal region, a conserved Region I (RI), a junctional region, 25–42 copies of major (NPNA) and minor repeats followed by a C-terminal domain. The recently approved malaria vaccine, RTS,S/AS01 contains NPNAx19 and the C-term...

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Detalles Bibliográficos
Autores principales: Langowski, Mark D., Khan, Farhat A., Savransky, Sofya, Brown, Dallas R., Balasubramaniyam, Arasu, Harrison, William B., Zou, Xiaoyan, Beck, Zoltan, Matyas, Gary R., Regules, Jason A., Miller, Robin, Soisson, Lorraine A., Batchelor, Adrian H., Dutta, Sheetij
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795123/
https://www.ncbi.nlm.nih.gov/pubmed/35087099
http://dx.doi.org/10.1038/s41541-022-00430-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795123/
https://www.ncbi.nlm.nih.gov/pubmed/35087099
http://dx.doi.org/10.1038/s41541-022-00430-y

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