Characterization of a novel non-steroidal glucocorticoid receptor agonist optimized for topical treatment

Glucocorticoids (GCs) are commonly used topical treatments for skin diseases but are associated with both local and systemic side effects. In this study, we describe a selective non-steroidal glucocorticoid receptor (GR) agonist for topical use, LEO 134310, which is rapidly deactivated in the blood...

Descripción completa

Detalles Bibliográficos
Autores principales: Eirefelt, Stefan, Stahlhut, Martin, Svitacheva, Naila, Carnerup, Martin A., Da Rosa, Joel Mauricio Correa, Ewald, David Adrian, Marstrand, Troels T., Krogh-Madsen, Mikkel, Dünstl, Georg, Dack, Kevin Neil, Ollerstam, Anna, Norsgaard, Hanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795149/
https://www.ncbi.nlm.nih.gov/pubmed/35087193
http://dx.doi.org/10.1038/s41598-022-05471-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795149/
https://www.ncbi.nlm.nih.gov/pubmed/35087193
http://dx.doi.org/10.1038/s41598-022-05471-w

Ejemplares similares