Cargando…

High-throughput platform for yeast morphological profiling predicts the targets of bioactive compounds

Morphological profiling is an omics-based approach for predicting intracellular targets of chemical compounds in which the dose-dependent morphological changes induced by the compound are systematically compared to the morphological changes in gene-deleted cells. In this study, we developed a reliab...

Descripción completa

Detalles Bibliográficos
Autores principales: Ohnuki, Shinsuke, Ogawa, Itsuki, Itto-Nakama, Kaori, Lu, Fachuang, Ranjan, Ashish, Kabbage, Mehdi, Gebre, Abraham Abera, Yamashita, Masao, Li, Sheena C., Yashiroda, Yoko, Yoshida, Satoshi, Usui, Takeo, Piotrowski, Jeff S., Andrews, Brenda J., Boone, Charles, Brown, Grant W., Ralph, John, Ohya, Yoshikazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795194/
https://www.ncbi.nlm.nih.gov/pubmed/35087094
http://dx.doi.org/10.1038/s41540-022-00212-1