Cargando…
High-throughput platform for yeast morphological profiling predicts the targets of bioactive compounds
Morphological profiling is an omics-based approach for predicting intracellular targets of chemical compounds in which the dose-dependent morphological changes induced by the compound are systematically compared to the morphological changes in gene-deleted cells. In this study, we developed a reliab...
Autores principales: | Ohnuki, Shinsuke, Ogawa, Itsuki, Itto-Nakama, Kaori, Lu, Fachuang, Ranjan, Ashish, Kabbage, Mehdi, Gebre, Abraham Abera, Yamashita, Masao, Li, Sheena C., Yashiroda, Yoko, Yoshida, Satoshi, Usui, Takeo, Piotrowski, Jeff S., Andrews, Brenda J., Boone, Charles, Brown, Grant W., Ralph, John, Ohya, Yoshikazu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795194/ https://www.ncbi.nlm.nih.gov/pubmed/35087094 http://dx.doi.org/10.1038/s41540-022-00212-1 |
Ejemplares similares
-
Jerveratrum-Type Steroidal Alkaloids Inhibit β-1,6-Glucan Biosynthesis in Fungal Cell Walls
por: Kubo, Karen, et al.
Publicado: (2022) -
Defining Functions of Mannoproteins in Saccharomyces cerevisiae by High-Dimensional Morphological Phenotyping
por: Ghanegolmohammadi, Farzan, et al.
Publicado: (2021) -
High-dimensional single-cell phenotyping reveals extensive haploinsufficiency
por: Ohnuki, Shinsuke, et al.
Publicado: (2018) -
Genetic profiling of protein burden and nuclear export overload
por: Kintaka, Reiko, et al.
Publicado: (2020) -
A microfluidic device to acquire high-magnification microphotographs of yeast cells
por: Ohnuki, Shinsuke, et al.
Publicado: (2009)