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3′mRNA sequencing reveals pro-regenerative properties of c5ar1 during resolution of murine acetaminophen-induced liver injury

Murine acetaminophen-induced acute liver injury (ALI) serves as paradigmatic model for drug-induced hepatic injury and regeneration. As major cause of ALI, acetaminophen overdosing is a persistent therapeutic challenge with N-acetylcysteine clinically used to ameliorate parenchymal necrosis. To iden...

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Detalles Bibliográficos
Autores principales: Gonther, Sina, Bachmann, Malte, Goren, Itamar, Huard, Arnaud, Weigert, Andreas, Köhl, Jörg, Mühl, Heiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795215/
https://www.ncbi.nlm.nih.gov/pubmed/35087052
http://dx.doi.org/10.1038/s41536-022-00206-x