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3′mRNA sequencing reveals pro-regenerative properties of c5ar1 during resolution of murine acetaminophen-induced liver injury
Murine acetaminophen-induced acute liver injury (ALI) serves as paradigmatic model for drug-induced hepatic injury and regeneration. As major cause of ALI, acetaminophen overdosing is a persistent therapeutic challenge with N-acetylcysteine clinically used to ameliorate parenchymal necrosis. To iden...
Autores principales: | Gonther, Sina, Bachmann, Malte, Goren, Itamar, Huard, Arnaud, Weigert, Andreas, Köhl, Jörg, Mühl, Heiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795215/ https://www.ncbi.nlm.nih.gov/pubmed/35087052 http://dx.doi.org/10.1038/s41536-022-00206-x |
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