Adult-induced genetic ablation distinguishes PDGFB roles in blood-brain barrier maintenance and development

Platelet-derived growth factor B (PDGFB) released from endothelial cells is indispensable for pericyte recruitment during angiogenesis in embryonic and postnatal organ growth. Constitutive genetic loss-of-function of PDGFB leads to pericyte hypoplasia and the formation of a sparse, dilated and venou...

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Detalles Bibliográficos
Autores principales: Vazquez-Liebanas, Elisa, Nahar, Khayrun, Bertuzzi, Giacomo, Keller, Annika, Betsholtz, Christer, Mäe, Maarja Andaloussi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795218/
https://www.ncbi.nlm.nih.gov/pubmed/34689641
http://dx.doi.org/10.1177/0271678X211056395

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795218/
https://www.ncbi.nlm.nih.gov/pubmed/34689641
http://dx.doi.org/10.1177/0271678X211056395

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