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Adult-induced genetic ablation distinguishes PDGFB roles in blood-brain barrier maintenance and development

Platelet-derived growth factor B (PDGFB) released from endothelial cells is indispensable for pericyte recruitment during angiogenesis in embryonic and postnatal organ growth. Constitutive genetic loss-of-function of PDGFB leads to pericyte hypoplasia and the formation of a sparse, dilated and venou...

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Detalles Bibliográficos
Autores principales:	Vazquez-Liebanas, Elisa, Nahar, Khayrun, Bertuzzi, Giacomo, Keller, Annika, Betsholtz, Christer, Mäe, Maarja Andaloussi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2021
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795218/ https://www.ncbi.nlm.nih.gov/pubmed/34689641 http://dx.doi.org/10.1177/0271678X211056395

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