Bile acids attenuate PKM2 pathway activation in proinflammatory microglia

Glycolysis is the metabolic pathway that converts glucose into pyruvate. Central nervous system (CNS) pathologies, such as spinal cord injury (SCI) and ischemia, are accompanied by an increase of the glycolytic pathway in the damaged areas as part of the inflammatory response. Pyruvate kinase is a k...

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Detalles Bibliográficos
Autores principales: Romero-Ramírez, Lorenzo, García-Rama, Concepción, Wu, Siyu, Mey, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795255/
https://www.ncbi.nlm.nih.gov/pubmed/35087114
http://dx.doi.org/10.1038/s41598-022-05408-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795255/
https://www.ncbi.nlm.nih.gov/pubmed/35087114
http://dx.doi.org/10.1038/s41598-022-05408-3

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