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Intranasal calcitonin gene-related peptide administration impairs fear memory retention in mice through the PKD/p-HDAC5/Npas4 pathway
The calcitonin gene-related peptide (CGRP) suppresses fear memory retention in mice. Although intracerebroventricular administration of CGRP alters the fear memory processes, making it a promising therapeutic strategy for post-traumatic stress disorder (PTSD), direct brain injection into patients is...
Autores principales: | Hashikawa-Hobara, Narumi, Yoneyama, Yoshikazu, Fujiwara, Kyoushiro, Hashikawa, Naoya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795377/ https://www.ncbi.nlm.nih.gov/pubmed/35087146 http://dx.doi.org/10.1038/s41598-022-05518-y |
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