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Procalcitonin is expressed in osteoblasts and limits bone resorption through inhibition of macrophage migration during intermittent PTH treatment

Intermittent injections of parathyroid hormone (iPTH) are applied clinically to stimulate bone formation by osteoblasts, although continuous elevation of parathyroid hormone (PTH) primarily results in increased bone resorption. Here, we identified Calca, encoding the sepsis biomarker procalcitonin (...

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Detalles Bibliográficos
Autores principales: Baranowsky, Anke, Jahn, Denise, Jiang, Shan, Yorgan, Timur, Ludewig, Peter, Appelt, Jessika, Albrecht, Kai K., Otto, Ellen, Knapstein, Paul, Donat, Antonia, Winneberger, Jack, Rosenthal, Lana, Köhli, Paul, Erdmann, Cordula, Fuchs, Melanie, Frosch, Karl-Heinz, Tsitsilonis, Serafeim, Amling, Michael, Schinke, Thorsten, Keller, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795393/
https://www.ncbi.nlm.nih.gov/pubmed/35087025
http://dx.doi.org/10.1038/s41413-021-00172-y