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Procalcitonin is expressed in osteoblasts and limits bone resorption through inhibition of macrophage migration during intermittent PTH treatment
Intermittent injections of parathyroid hormone (iPTH) are applied clinically to stimulate bone formation by osteoblasts, although continuous elevation of parathyroid hormone (PTH) primarily results in increased bone resorption. Here, we identified Calca, encoding the sepsis biomarker procalcitonin (...
Autores principales: | Baranowsky, Anke, Jahn, Denise, Jiang, Shan, Yorgan, Timur, Ludewig, Peter, Appelt, Jessika, Albrecht, Kai K., Otto, Ellen, Knapstein, Paul, Donat, Antonia, Winneberger, Jack, Rosenthal, Lana, Köhli, Paul, Erdmann, Cordula, Fuchs, Melanie, Frosch, Karl-Heinz, Tsitsilonis, Serafeim, Amling, Michael, Schinke, Thorsten, Keller, Johannes |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795393/ https://www.ncbi.nlm.nih.gov/pubmed/35087025 http://dx.doi.org/10.1038/s41413-021-00172-y |
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