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Efficacy of an inactivated Zika vaccine against virus infection during pregnancy in mice and marmosets

Zika virus (ZIKV) is a mosquito-borne arbovirus that can cause severe congenital birth defects. The utmost goal of ZIKV vaccines is to prevent both maternal-fetal infection and congenital Zika syndrome. A Zika purified inactivated virus (ZPIV) was previously shown to be protective in non-pregnant mi...

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Detalles Bibliográficos
Autores principales: Kim, In-Jeong, Lanthier, Paula A., Clark, Madeline J., De La Barrera, Rafael A., Tighe, Michael P., Szaba, Frank M., Travis, Kelsey L., Low-Beer, Timothy C., Cookenham, Tres S., Lanzer, Kathleen G., Bernacki, Derek T., Johnson, Lawrence L., Schneck, Amanda A., Ross, Corinna N., Tardif, Suzette D., Layne-Colon, Donna, Mdaki, Stephanie D., Dick, Edward J., Chuba, Colin, Gonzalez, Olga, Brasky, Kathleen M., Dutton, John, Rutherford, Julienne N., Coffey, Lark L., Singapuri, Anil, Martin, Claudia Sanchez San, Chiu, Charles Y., Thomas, Stephen J., Modjarrad, Kayvon, Patterson, Jean L., Blackman, Marcia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795414/
https://www.ncbi.nlm.nih.gov/pubmed/35087081
http://dx.doi.org/10.1038/s41541-021-00426-0