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Pre-existing antibodies directed against a tetramerizing domain enhance the immune response against artificially stabilized soluble tetrameric influenza neuraminidase

The neuraminidase (NA) is an abundant antigen at the surface of influenza virions. Recent studies have highlighted the immune-protective potential of NA against influenza and defined anti-NA antibodies as an independent correlate of protection. Even though NA head domain changes at a slightly slower...

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Detalles Bibliográficos
Autores principales: Catani, João Paulo Portela, Job, Emma R., Ysenbaert, Tine, Smet, Anouk, Ray, Satyajit, LaRue, Lauren, Stegalkina, Svetlana, Barro, Mario, Vogel, Thorsten U., Saelens, Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795415/
https://www.ncbi.nlm.nih.gov/pubmed/35087067
http://dx.doi.org/10.1038/s41541-022-00435-7